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One way slab only acts one way if you have stiff beams (a rule of thumb would be depth at least 3 times depth of slab) all around it. If you don't have beams and a slab is 32ft*12ft directly supported on four columns, your main bending would be along the length of slab. The reason why one way slabs have main reinfo in short direction is deformation compatibility. Ayesha and Rana have summed your question about reinforcement nicely. The perpendicular thing is incorrect. You need to see local axis. Thanks.